Phosphoinositide 3-kinase in Health and Disease
Volume 1| By: | null |
| Publisher: | Springer Nature |
| Print ISBN: | 9783642136627 |
| eText ISBN: | 9783642136634 |
| Edition: | 0 |
| Copyright: | 2011 |
| Format: | Page Fidelity |
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Table of Contents
From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here we give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here