NF-κB-Related Genetic Diseases
| By: | Gilles Courtois; Alessandra Pescatore; Jérémie Gautheron; Francesca Fusco; Matilde Valeria Ursini; A |
| Publisher: | Springer Nature |
| Print ISBN: | 9783319258485 |
| eText ISBN: | 9783319258508 |
| Edition: | 0 |
| Copyright: | 2016 |
| Format: | Page Fidelity |
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This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.