TRAIL
| By: | Litwack, Gerald |
| Publisher: | Elsevier S & T |
| Print ISBN: | 9780127098678 |
| eText ISBN: | 9780080522876 |
| Edition: | 0 |
| Format: | Page Fidelity |
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The discovery of TRAIL (TNF Related Apoptosis Inducing Ligand), also referred to as Apo-2, is in an era of intense research because TRAIL induces many cancer cells to undergo programmed cell death (apoptosis), while having no effect on normal cells. This important protein deserves extensive review at a formative time in the devlopement of our knowledge concerning its mechanism of action and the ways in which it can be used as a cancer chemotherapeutic agent. Consequently, this voume reviews the current status of research on TRAIL.
Selected Contents:
* Crystal Structure of RANK Ligand involved in bone metabolism
* Promoter of TRAIL-R2 Gene
* Monoclonal Antibodies against TRAIL
* Modulation of TRAIL signaling complex
* TRAIL in the airways
* FLIP Protein and TRAIL-Induced Apoptosis
* TRAIL and Ceramide
* TRAIL and Viral Infection
* TRAIL and Malignant Glioma